SQL Server uses the port 1433 as its standard listening port. Hackers know this and will use it to more easily hack into your SQL environment. Because of this, many DBAs will choose to not use the standard SQL port of 1433 for their SQL environment and will change the port to a ‘non-standard’ port.
Since SQL diagnostic manager uses much of the instrumentation of SQL server to perform it’s monitoring, it is required to configure the product slightly different if your SQL server instance is not using standard ports
This video describes how you would set up SQL diagnostic manager to perform monitoring even if the SQL server instance is using different ports than the standard 1433 port.
Other Resources: